SubtiBank SubtiBank
ylnD [2018-02-09T09:00:41.000Z]
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ylnD [2018-02-09T09:00:41.000Z]

probable uroporphyrin-III C-methyltransferase
Locus
BSU15610
Isoelectric point
5.75
Molecular weight
28.37 kDa
Protein length
257 aa Sequence Blast
Gene length
771 bp Sequence Blast
Function
siroheme biosynthesis , sulfite reduction
Product
probable uroporphyrin-III C-methyltransferase
Essential
no
E.C.
2.1.1.107
Synonyms
sumT
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Additional metabolic pathways → Biosynthesis of cofactors → Biosynthesis of heme/ siroheme

    • Gene

    Coordinates
    1,634,061 → 1,634,834

    The protein

    Paralogous protein(s)

  • NasF (N-terminal domain)

    • Structure

  • 1PJQ (CysG from Salmonella enterica, 46% identity) PubMed

    • Expression and Regulation

    Operons

    Genes
    cysH-cysP-sat-cysC-ylnD-sirB-ylnF
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

    • Regulatory mechanism

  • CymR: repression, in CymR regulon
  • S-box: termination, the S-box riboswitch binds S-adenosylmethionine resulting in termination PubMed, in S-box

    • Regulation

  • induced by methionine starvation (S-box) PubMed
  • the S-box RNA is degraded by RNase Y PubMed
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    Biological materials

    Mutant

  • MGNA-B368 (ylnD::erm), available at the NBRP B. subtilis, Japan
  • BKE15610 (ΔylnD::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCGTATTTCCCCCGATCT, downstream forward: _UP4_GATTTAAGCGAGGCGTTGTA
  • BKK15610 (ΔylnD::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCGTATTTCCCCCGATCT, downstream forward: _UP4_GATTTAAGCGAGGCGTTGTA

    • References

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